/* SG_V1_SHARED_UTILITIES_START */
main{margin:0;padding:0;border:0;font:inherit;font-size:100%;vertical-align:baseline;}
section{width:100%;}
.sg-only-desktop{display:none !important;}
.sg-only-mobile{display:revert;}
@media (min-width:1024px){.sg-only-desktop{display:revert !important;}.sg-only-mobile{display:none !important;}}
@media (min-width:1024px){.sg-only-desktop.sg-form-block{display:flex !important;}}
@media (max-width:1023.98px){.sg-only-mobile.sg-form-block{display:flex !important;}}
.sg-img-bg-node{background-size:cover;background-position:center;background-repeat:no-repeat;}
sup.sg-sup-marker{font-size:0.7em !important;line-height:1;vertical-align:super;align-self:flex-start;}
.sg-mb0{margin-bottom:0 !important;}
p{overflow-wrap:break-word;}
p:last-child,p:only-child{margin-bottom:0 !important;}
.form-group{width:100%;margin:0;}
.form-control{width:100%;display:block;}
.control-label{display:block;}
.sg-asset__placeholder{width:100%;height:100%;min-height:inherit;display:flex;align-items:center;justify-content:center;border:1px dashed #cbd5e1;background:#f8fafc;color:#475569;font:12px/1.3 Arial,sans-serif;text-transform:uppercase;letter-spacing:.04em;}
.sg-top-chrome{width:100%;display:flex;flex-direction:column;}
.sg-top-chrome .sg-global{width:100%;}
.sg-top-chrome--sticky{position:sticky;top:0;z-index:30;}
@media (min-width:1024px){[data-id="headerRow"].sg-top-chrome [data-id="pdfRow"]:not(.sg-only-mobile),#sg-top-chrome [data-id="pdfRow"]:not(.sg-only-mobile){display:flex !important;align-items:center;}}
@media (max-width:1023.98px){[data-id="headerRow"].sg-top-chrome [data-id="pdfRow"]:not(.sg-only-desktop),#sg-top-chrome [data-id="pdfRow"]:not(.sg-only-desktop){display:flex !important;align-items:center;}}
[data-id="headerRow"].sg-top-chrome [data-id="pdfRow"] .link-pdf,#sg-top-chrome [data-id="pdfRow"] .link-pdf{cursor:pointer;width:auto;flex:0 0 auto;display:inline-flex;align-items:center;}
[data-id="headerRow"].sg-top-chrome [data-id="pdfRow"] .spacer,#sg-top-chrome [data-id="pdfRow"] .spacer{flex:0 0 auto;align-self:center;border-left:1px solid currentColor;}
#content,[data-id="content"],#contentWrapper,[data-id="contentWrapper"],[data-id="maxWidthContent"]{border:0;border-image:none;border-image-width:0;box-shadow:none;}
/* SG_V1_SHARED_UTILITIES_END */



/* SG_V1_ISI_CONTENT_CSS_START */
[data-id="isiDrawerContent"] .sg-isi-dsk-tx-1{font-family:'Lato';font-size:14px;font-weight:700;line-height:18px;text-align:left;color:rgb(83, 85, 84);-webkit-text-fill-color:inherit;-webkit-background-clip:unset;background-clip:unset;margin-bottom:12px;width:100%;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li{display:flex;flex-direction:column;gap:var(--sg-gap,0);align-items:stretch;width:100%;--sg-gap:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul{margin:0;padding-left:0;display:flex;flex-direction:column;gap:4px;list-style:none;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li{margin:0;}
[data-id="isiDrawerContent"] .sg-isi-dsk-tx-2{font-family:'Lato';font-size:14px;font-weight:400;line-height:18px;text-align:left;color:rgb(83, 85, 84);-webkit-text-fill-color:inherit;-webkit-background-clip:unset;background-clip:unset;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(1)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(1){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(2)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(2){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(3)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(3){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(4)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(4){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(5)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(5){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(6)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(6){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(6) > ul > li:nth-child(1)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;box-sizing:border-box;background-color:transparent;border:1px solid rgb(83,85,84);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(6) > ul > li:nth-child(1){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(6) > ul > li:nth-child(2)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;box-sizing:border-box;background-color:transparent;border:1px solid rgb(83,85,84);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(6) > ul > li:nth-child(2){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(7)::before{content:"";position:absolute;left:0px;top:0px;display:block;width:4px;height:18px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(7){display:block;position:relative;padding-left:8px;min-height:18px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(8)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(8){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .sg-isi-dsk-tx-3{font-family:'Lato';font-size:14px;font-weight:400;line-height:18px;text-align:left;color:rgb(83, 85, 84);-webkit-text-fill-color:inherit;-webkit-background-clip:unset;background-clip:unset;margin-bottom:12px;width:100%;}
[data-id="isiDrawerContent"] .sg-isi-dsk-tx-4{font-family:'Lato';font-size:14px;font-weight:700;line-height:18px;text-align:left;color:rgb(253, 107, 13);-webkit-text-fill-color:inherit;-webkit-background-clip:unset;background-clip:unset;margin-bottom:12px;width:100%;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2{display:flex;flex-direction:column;gap:var(--sg-gap,0);align-items:stretch;width:100%;--sg-gap:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul{margin:0;padding-left:0;display:flex;flex-direction:column;gap:4px;list-style:none;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li{margin:0;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(1)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(1){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(2)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(2){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(3)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(3){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(4)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(4){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(5)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(5){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(6)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(6){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(7)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(7){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3{display:flex;flex-direction:column;gap:var(--sg-gap,0);align-items:stretch;width:100%;--sg-gap:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul{margin:0;padding-left:0;display:flex;flex-direction:column;gap:4px;list-style:none;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li{margin:0;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(1)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(1){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(2)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(2){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(3)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(3){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(4)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(4){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(5)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(5){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(6)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(6){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-4{display:flex;flex-direction:column;gap:var(--sg-gap,0);align-items:stretch;width:100%;--sg-gap:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-4 > ul{margin:0;padding-left:0;display:flex;flex-direction:column;gap:4px;list-style:none;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-4 > ul > li{margin:0;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-4 > ul > li:nth-child(1)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-4 > ul > li:nth-child(1){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-4 > ul > li:nth-child(2)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-4 > ul > li:nth-child(2){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-4 > ul > li:nth-child(3)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-4 > ul > li:nth-child(3){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li{margin-top:14px;}
[data-id="isiDrawerContent"] .tell-your-healthcare-provider-about-all-{margin-top:14px;}
[data-id="isiDrawerContent"] .how-should-i-take-calquence{margin-top:14px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2{margin-top:14px;}
[data-id="isiDrawerContent"] .what-are-the-possible-side-effects-of-ca{margin-top:14px;}
[data-id="isiDrawerContent"] .calquence-can-cause-serious-side-effects{margin-top:14px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3{margin-top:14px;}
[data-id="isiDrawerContent"] .the-most-common-side-effects-of-calquenc{margin-top:14px;}
[data-id="isiDrawerContent"] .these-are-not-all-the-possible-side-effe{margin-top:14px;}
[data-id="isiDrawerContent"] .what-is-calquence{margin-top:14px;}
[data-id="isiDrawerContent"] .calquence-is-a-prescription-medicine-use{margin-top:14px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-4{margin-top:14px;}
[data-id="isiDrawerContent"] .it-is-not-known-if-calquence-is-safe-and{margin-top:14px;}
[data-id="isiDrawerContent"] .please-see-full-prescribing-information-{margin-top:14px;}
[data-id="isiDrawerContent"] .you-may-report-side-effects-related-to-a{margin-top:14px;}
[data-id="isiDrawerContent"] .sg-isi-dsk-tx-override-1{gap:4px}
[data-id="isiDrawerContent"] .sg-isi-dsk-tx-override-2{color:rgb(253, 107, 13)}
[data-id="isiDrawerContent"] .sg-isi-dsk-tx-override-3{font-style:italic;color:rgb(83, 85, 84)}
[data-id="isiDrawerContent"] .sg-isi-dsk-tx-override-4{font-style:italic}
[data-id="isiDrawerContent"] .sg-isi-mob-tx-1{font-family:'Lato';font-size:14px;font-weight:700;line-height:18px;text-align:left;color:rgb(253, 107, 13);-webkit-text-fill-color:inherit;-webkit-background-clip:unset;background-clip:unset;align-self:stretch;margin-bottom:0 !important;width:100%;}
[data-id="isiDrawerContent"] .sg-isi-mob-tx-2{font-family:'Lato';font-size:14px;font-weight:700;line-height:18px;text-align:left;color:rgb(83, 85, 84);-webkit-text-fill-color:inherit;-webkit-background-clip:unset;background-clip:unset;align-self:stretch;margin-bottom:0 !important;width:100%;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li{display:flex;flex-direction:column;gap:var(--sg-gap,0);align-items:stretch;width:100%;align-self:stretch;--sg-gap:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul{margin:0;padding-left:0;display:flex;flex-direction:column;gap:4px;list-style:none;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li{margin:0;}
[data-id="isiDrawerContent"] .sg-isi-mob-tx-3{font-family:'Lato';font-size:14px;font-weight:400;line-height:18px;text-align:left;color:rgb(83, 85, 84);-webkit-text-fill-color:inherit;-webkit-background-clip:unset;background-clip:unset;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(1)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(1){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(2)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(2){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(3)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(3){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(4)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(4){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(5)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(5){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(6)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(6){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(6) > ul > li:nth-child(1)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;box-sizing:border-box;background-color:transparent;border:1px solid rgb(83,85,84);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(6) > ul > li:nth-child(1){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(6) > ul > li:nth-child(2)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;box-sizing:border-box;background-color:transparent;border:1px solid rgb(83,85,84);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(6) > ul > li:nth-child(2){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(7)::before{content:"";position:absolute;left:0px;top:0px;display:block;width:4px;height:18px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(7){display:block;position:relative;padding-left:8px;min-height:18px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(8)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li > ul > li:nth-child(8){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .sg-isi-mob-tx-4{font-family:'Lato';font-size:14px;font-weight:400;line-height:18px;text-align:left;color:rgb(83, 85, 84);-webkit-text-fill-color:inherit;-webkit-background-clip:unset;background-clip:unset;align-self:stretch;margin-bottom:0 !important;width:100%;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2{display:flex;flex-direction:column;gap:var(--sg-gap,0);align-items:stretch;width:100%;align-self:stretch;--sg-gap:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul{margin:0;padding-left:0;display:flex;flex-direction:column;gap:4px;list-style:none;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li{margin:0;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(1)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(1){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(2)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(2){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(3)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(3){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(4)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(4){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(5)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(5){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(6)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(6){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(7)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-2 > ul > li:nth-child(7){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3{display:flex;flex-direction:column;gap:var(--sg-gap,0);align-items:stretch;width:100%;align-self:stretch;--sg-gap:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul{margin:0;padding-left:0;display:flex;flex-direction:column;gap:4px;list-style:none;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li{margin:0;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(1)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(1){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(2)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(2){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(3)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(3){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(4)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(4){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(5)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(5){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(6)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-3 > ul > li:nth-child(6){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-4{display:flex;flex-direction:column;gap:var(--sg-gap,0);align-items:stretch;width:100%;align-self:stretch;--sg-gap:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-4 > ul{margin:0;padding-left:0;display:flex;flex-direction:column;gap:4px;list-style:none;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-4 > ul > li{margin:0;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-4 > ul > li:nth-child(1)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-4 > ul > li:nth-child(1){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-4 > ul > li:nth-child(2)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-4 > ul > li:nth-child(2){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-4 > ul > li:nth-child(3)::before{content:"";position:absolute;left:0px;top:7px;display:block;width:4px;height:4px;border-radius:999px;background-color:rgb(253, 107, 13);}
[data-id="isiDrawerContent"] .ul-sample-bullet-list-with-sub-bullet-li-4 > ul > li:nth-child(3){display:block;position:relative;padding-left:8px;min-height:4px;}
[data-id="isiDrawerContent"] .astrazeneca-logo-1{flex:0 0 45px;width:173px;max-width:100%;height:45px;}
[data-id="isiDrawerContent"] .astrazeneca-logo-1 > .sg-export-crop > picture > img{width:173px;max-width:100%;aspect-ratio:173 / 45;height:auto;}
[data-id="isiDrawerContent"] .sg-isi-mob-tx-override-1{gap:4px}
[data-id="isiDrawerContent"] .sg-isi-mob-tx-override-2{color:rgb(253, 107, 13)}
[data-id="isiDrawerContent"] .sg-isi-mob-tx-override-3{font-style:italic;color:rgb(83, 85, 84)}
[data-id="isiDrawerContent"] .sg-isi-mob-tx-override-4{font-style:italic}
@media (max-width:1023.98px){
[data-id="isiDrawerContent"] .inner-content{display:flex;flex-direction:column;gap:var(--sg-gap,0);align-items:stretch;width:100%;align-self:stretch;--sg-gap:32px;padding:8px 24px 32px 24px;max-width:100%;}
[data-id="isiDrawerContent"] .isi-content{display:flex;flex-direction:column;gap:var(--sg-gap,0);align-items:stretch;width:100%;align-self:stretch;--sg-gap:14px;max-width:100%;}
[data-id="isiDrawerContent"] .footer{display:flex;flex-direction:column;gap:8px;align-items:stretch;width:100%;align-self:stretch;--sg-gap:8px;max-width:100%;}
}
/* SG_V1_ISI_CONTENT_CSS_END */

/* SG_V1_ISI_HEADER_CSS_START */
[data-id="isiDrawerHeader"] .isidrawerheaderinner{display:flex;flex-direction:row;justify-content:flex-end;align-items:center;width:100%;}
[data-id="isiDrawerHeader"] .sg-isi-dsk-tx-5{font-family:'Lato';font-size:14px;font-weight:700;line-height:18px;text-align:left;color:rgb(253, 107, 13);-webkit-text-fill-color:inherit;-webkit-background-clip:unset;background-clip:unset;flex:1 1 0;margin-bottom:0 !important;max-width:none;width:auto;}
[data-id="isiDrawerHeader"] .isi-button{flex:0 0 30px;width:30px;max-width:100%;height:30px;align-items:flex-start;}
[data-id="isiDrawerHeader"] .isi-button > .sg-export-crop > picture > img{width:30px;max-width:100%;aspect-ratio:30 / 30;height:auto;}
@media (min-width:1024px){
[data-id="isiDrawerHeader"] .isidrawerheaderinner{gap:var(--sg-gap,0);--sg-gap:10px;max-width:992px;padding:2px 0px 2px 0px;}
[data-id="isiDrawerHeader"] .isi-button{align-self:center;}
}
@media (max-width:1023.98px){
[data-id="isiDrawerHeader"] .isidrawerheaderinner{max-width:100%;}
}
/* SG_V1_ISI_HEADER_CSS_END */

/* SG_V1_SHELL_TEXT_STYLE_START */
[data-id="headerRow"] .link-pdf,#sg-top-chrome .link-pdf{font-family:'Lato';font-size:14px;font-weight:700;line-height:24px;text-align:left;color:rgb(255, 255, 255);-webkit-text-fill-color:inherit;-webkit-background-clip:unset;background-clip:unset}
/* SG_V1_SHELL_TEXT_STYLE_END */

/* SG_ISI_STYLE_START */
@media (max-width:1023.98px){
  [data-id="isiDrawer"]{background-color:rgb(255, 255, 255);box-shadow:0 -2px 8px rgba(0,0,0,0.20);}
  [data-id="isiDrawerHeader"]{color:rgb(51, 51, 51);padding:8px 24px 8px 24px;height:46px;border:none;background:none;background-color:rgb(255, 255, 255);display:flex;align-items:center;justify-content:space-between;width:100%;gap:0px;}
  [data-id="isiDrawerHeader"] .inner-content{gap:0px;}
  [data-id="isiDrawerHeader"] .text-bold{flex:1 1 0;min-width:0;display:flex;flex-direction:row;align-items:center;justify-content:space-between;}
  [data-id="isiDrawerHeader"] .expanded-status{display:inline-flex;align-items:center;flex:0 0 auto;}
  [data-id="isiDrawerHeader"] .expanded-status .sg-isi-caret-fallback{display:inline-flex;align-items:center;justify-content:center;width:100%;height:100%;font-family:Arial,sans-serif;font-size:24px;line-height:1;font-weight:700;}
  [data-id="isiDrawerHeader"] .expanded-status .expand-symbol:not(.sg-caret-has-svg),[data-id="isiDrawerHeader"] .expanded-status .collapse-symbol:not(.sg-caret-has-svg){background-color:rgb(54, 201, 193);color:rgb(255, 255, 255);box-shadow:0 0 4px rgba(0,0,0,0.4);width:30px;height:30px;border-radius:50%;display:inline-flex;align-items:center;justify-content:center;flex:0 0 auto;}
  [data-id="isiDrawerHeader"] .expanded-status .expand-symbol.sg-caret-has-svg,[data-id="isiDrawerHeader"] .expanded-status .collapse-symbol.sg-caret-has-svg{background:none;box-shadow:none;width:30px;height:30px;align-items:center;justify-content:center;align-self:center;line-height:0;flex:0 0 auto;}
  [data-id="isiDrawerHeader"] .expanded-status .expand-symbol.sg-caret-has-svg > .sg-isi-caret-svg,[data-id="isiDrawerHeader"] .expanded-status .collapse-symbol.sg-caret-has-svg > .sg-isi-caret-svg{display:block;width:100%;height:100%;object-fit:contain;}
  [data-id="isiDrawerContent"]{display:flex;flex-direction:column;background-color:rgb(255, 255, 255);padding-left:0;padding-right:0;max-width:634px;width:100%;margin-left:auto;margin-right:auto;box-sizing:border-box;scrollbar-width:none;}
  [data-id="isiDrawerContent"]::-webkit-scrollbar{display:none;}
  [data-id="isiDrawerContent"] .sg-ul.sg-ul--bullet{list-style:none;margin:0;padding:0;padding-left:0px;display:flex;flex-direction:column;gap:10px;}
  [data-id="isiDrawerContent"] .sg-ul.sg-ul--bullet > .sg-li{display:block;position:relative;padding-left:18px;}
  [data-id="isiDrawerContent"] .sg-ul.sg-ul--bullet > .sg-li::before{content:"";position:absolute;left:0;top:10px;display:block;width:6px;height:6px;border-radius:999px;background-color:currentColor;}
  [data-id="isiDrawerContent"] .sg-ul.sg-ul--bullet .sg-ul.sg-ul--sub{list-style:none;margin:0;padding:0;padding-left:0px;display:flex;flex-direction:column;gap:10px;padding-left:0;}
  [data-id="isiDrawerContent"] .sg-ul.sg-ul--bullet .sg-ul.sg-ul--sub > .sg-li::before{width:8px;height:8px;left:0;top:9px;border-radius:999px;background-color:currentColor;}
}
@media (min-width:1024px){
  [data-id="isiDrawer"]{background-color:rgb(255, 255, 255);box-shadow:0 -2px 8px rgba(0,0,0,0.20);}
  [data-id="isiDrawerHeader"]{color:rgb(253, 107, 13);font-family:'Lato';font-size:14px;font-weight:700;line-height:18px;letter-spacing:0px;text-transform:none;padding:8px 0px 0px 0px;height:42px;border:none;background:none;background-color:rgb(255, 255, 255);display:flex;align-items:center;justify-content:space-between;width:100%;gap:10px;}
  [data-id="isiDrawerHeader"] .inner-content{max-width:992px;margin-left:auto;margin-right:auto;gap:10px;}
  [data-id="isiDrawerHeader"] .text-bold{flex:1 1 0;min-width:0;display:flex;flex-direction:row;align-items:center;justify-content:space-between;}
  [data-id="isiDrawerHeader"] .expanded-status{display:inline-flex;align-items:center;flex:0 0 auto;}
  [data-id="isiDrawerHeader"] .expanded-status .sg-isi-caret-fallback{display:inline-flex;align-items:center;justify-content:center;width:100%;height:100%;font-family:Arial,sans-serif;font-size:24px;line-height:1;font-weight:700;}
  [data-id="isiDrawerHeader"] .expanded-status .expand-symbol:not(.sg-caret-has-svg),[data-id="isiDrawerHeader"] .expanded-status .collapse-symbol:not(.sg-caret-has-svg){background-color:rgb(54, 201, 193);color:rgb(255, 255, 255);box-shadow:0 0 4px rgba(0,0,0,0.4);width:30px;height:30px;border-radius:50%;display:inline-flex;align-items:center;justify-content:center;flex:0 0 auto;}
  [data-id="isiDrawerHeader"] .expanded-status .expand-symbol.sg-caret-has-svg,[data-id="isiDrawerHeader"] .expanded-status .collapse-symbol.sg-caret-has-svg{background:none;box-shadow:none;width:30px;height:30px;align-items:center;justify-content:center;align-self:center;line-height:0;flex:0 0 auto;}
  [data-id="isiDrawerHeader"] .expanded-status .expand-symbol.sg-caret-has-svg > .sg-isi-caret-svg,[data-id="isiDrawerHeader"] .expanded-status .collapse-symbol.sg-caret-has-svg > .sg-isi-caret-svg{display:block;width:100%;height:100%;object-fit:contain;}
  [data-id="isiDrawerContent"]{display:flex;flex-direction:column;background-color:rgb(255, 255, 255);align-items:center;scrollbar-width:none;}
  [data-id="isiDrawerContent"]::-webkit-scrollbar{display:none;}
  [data-id="isiDrawerContent"] .sg-ul.sg-ul--bullet{list-style:none;margin:0;padding:0;padding-left:0px;display:flex;flex-direction:column;gap:10px;}
  [data-id="isiDrawerContent"] .sg-ul.sg-ul--bullet > .sg-li{display:block;position:relative;padding-left:18px;}
  [data-id="isiDrawerContent"] .sg-ul.sg-ul--bullet > .sg-li::before{content:"";position:absolute;left:0;top:10px;display:block;width:6px;height:6px;border-radius:999px;background-color:currentColor;}
  [data-id="isiDrawerContent"] .sg-ul.sg-ul--bullet .sg-ul.sg-ul--sub{list-style:none;margin:0;padding:0;padding-left:0px;display:flex;flex-direction:column;gap:10px;padding-left:0;}
  [data-id="isiDrawerContent"] .sg-ul.sg-ul--bullet .sg-ul.sg-ul--sub > .sg-li::before{width:8px;height:8px;left:0;top:9px;border-radius:999px;background-color:currentColor;}
}
/* SG_ISI_STYLE_END */